Per this study, reduced endotoxin-producing bacteria and increased gut barrier-protecting bacteria in the gut improved gut barrier function, reduced serum endotoxin load, and alleviated low-grade inflammation further strengthening the connection between gut-derived endotoxin and the pathogenesis of obesity-associated disorders in humans. Targeting gut microbiota via dietary intervention for reducing endotoxin load and inflammation may become a promising method for managing obesity and related metabolic disorders.
See the following link
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255291/
